A few words about Irregular Orbit's design. The look was inspired by early newspapers and broadsheets, though it didn't really turn out much like them at all, did it? The grey-scale color scheme is for that early television feel. A gaslight-era newspaper transmitted through primitive television technology -- what was I thinking?
Technically, I'm taking the user-hostile approach. The page is hard-sized for a 1024x768 display (with a bit of room to spare), and if you're running less, tough cookies -- you're going to be doing a little side-scrolling. Also, it will not render correctly in browsers that are not up to date in CSS compliance. NS4 on any platform is a trainwreck, and I have a report that IE5 on Mac9 is also a mess (I would be interested to hear how it does on more state of the art Macs). IE5 on Win fails to render the header and center column at quite the same width -- it handles padding incorrectly. Not sure about later versions of IE. However, it renders just fine on Mozilla or Opera, which have versions available for virtually all platforms (why would you want to run IE anyway, with its perpetually blossoming security bugs?). Useability, shmoosability -- I'm sorry, but I just don't care anymore. Life's too short and the tyranny of the lowest common denominator is a drag. If this doesn't look right in your browser, run one that works.